Manchester United have major injury concerns in defence as Nemanja Vidic and Wes Brown are reportedly doubtful for tonight’s Champions League semi-final first-leg in Barcelona.

Centre-back Vidic had missed training in the Nou Camp on Tuesday, and reports in Spain claimed that he had a stomach problem overnight that saw the Serbian taken to a hospital.

Brown, who has played mostly at right-back this season, also has an injury and the Red Devils boss Sir Alex Ferguson will wait until the last minute, with fit-again skipper Gary Neville said to be on stand-by.